ARG45594
anti-AKR1B10 antibody
anti-AKR1B10 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AKR1B10 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AKR1B10 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human AKR1B10. |
| Conjugation | Un-conjugated |
| Alternate Names | AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); ARP; AKR1B12; AKR1B11; HIS; ARL-1; Aldo-keto reductase family 1 member B10; ARL1; HSI; SI reductase; ALDRLn; EC 1.1.1.-; Aldose reductase-like; Small intestine reductase; Aldose reductase-related protein; hARP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 36 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O60218 Human Aldo-keto reductase family 1 member B10 |
|---|---|
| Gene Symbol | AKR1B10 |
| Gene Full Name | aldo-keto reductase family 1, member B10 (aldose reductase) |
| Background | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008] |
| Function | Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. [UniProt] |
| Cellular Localization | Lysosome; Secreted. [UniProt] |
| Calculated MW | 36 kDa |
| PTM | Acetylation. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG45594 anti-AKR1B10 antibody IHC-P image
Immunohistochemistry: Human intestinal cancer stained with ARG45594 anti-AKR1B10 antibody at 1 μg/ml dilution.
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ARG45594 anti-AKR1B10 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45594 anti-AKR1B10 antibody at 5 μg/ml dilution.
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ARG45594 anti-AKR1B10 antibody WB image
Western blot: A549 stained with ARG45594 anti-AKR1B10 antibody at 0.5 μg/ml dilution.
