ARG45714
anti-ALAS2 / ASB antibody
anti-ALAS2 / ASB antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ALAS2 / ASB |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ALAS2 / ASB |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human ALAS2 / ASB. |
| Conjugation | Un-conjugated |
| Alternate Names | ALAS2; 5'-Aminolevulinate Synthase 2; ALAS-E; ASB; 5-Aminolevulinate Synthase, Erythroid-Specific, Mitochondrial; Erythroid-Specific Delta-Aminolevulinate Synthase; Aminolevulinate, Delta-, Synthase 2; 5-Aminolevulinic Acid Synthase 2; Delta-Aminolevulinate Synthase 2; Delta-ALA Synthase 2; EC 2.3.1.37 47; ALASE; Aminolevulinate, Delta-, Synthase 2 (Sideroblastic/Hypochromic Anemia); Sideroblastic/Hypochromic Anemia; Delta-ALA Synthetase; SIDBA1; XLDPP; XLEPP; ANH1; XLSA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ALAS2 |
| Gene Full Name | 5'-Aminolevulinate Synthase 2 |
| Background | The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. [UniProt] |
| Cellular Localization | Membrane; Mitochondrion; Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 65 kDa |
Images (5) Click the Picture to Zoom In
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ARG45714 anti-ALAS2 / ASB antibody ICC/IF image
Immunofluorescence: PC-3 stained with ARG45714 anti-ALAS2 / ASB antibody at 5 μg/ml dilution.
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ARG45714 anti-ALAS2 / ASB antibody WB image
Western blot: 293T stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.
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ARG45714 anti-ALAS2 / ASB antibody FACS image
Flow Cytometry: K562 stained with ARG45714 anti-ALAS2 / ASB antibody at 1 µg/10^6 cells dilution.
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ARG45714 anti-ALAS2 / ASB antibody WB image
Western blot: Rat heart stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.
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ARG45714 anti-ALAS2 / ASB antibody WB image
Western blot: Mouse liver stained with ARG45714 anti-ALAS2 / ASB antibody at 0.5 μg/ml dilution.
