ARG54131

anti-ALDH2 antibody

anti-ALDH2 antibody for Western blot and Human,Mouse,Rat,Monkey,Hamster

Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody recognizes ALDH2
Tested Reactivity Hu, Ms, Rat, Hm, Mk
Tested Application WB
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name ALDH2
Antigen Species Human
Immunogen Purified recombinant human ALDH2 protein fragments expressed in E.coli
Conjugation Un-conjugated
Alternate Names EC 1.2.1.3; ALDH class 2; ALDM; ALDHI; Aldehyde dehydrogenase, mitochondrial; ALDH-E2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 56 kDa

Properties

Form Liquid
Purification Affinity purified
Buffer PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 4.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11669 Mouse ALDH2

GeneID: 217 Human ALDH2

GeneID: 29539 Rat ALDH2

Gene Symbol ALDH2
Gene Full Name aldehyde dehydrogenase 2 family (mitochondrial)
Background This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2011]
Cellular Localization Mitochondrion matrix.
Research Area Cell Biology and Cellular Response antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 56 kDa

Images (1) Click the Picture to Zoom In

  • ARG54131 anti-ALDH2 antibody WB image

    Western blot: 3T3 cell lysate stained with ARG54131 anti-ALDH2 antibody at 1:1000 dilution.