ARG45993
anti-AMBRA1 antibody
anti-AMBRA1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AMBRA1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AMBRA1 |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within the last 50 amino acids of human AMBRA1. |
| Conjugation | Un-conjugated |
| Alternate Names | AMBRA1; DCAF3; Activating molecule in BECN1-regulated autophagy protein 1; WDR94 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 143 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # A2AH22 Mouse Activating molecule in BECN1-regulated autophagy protein 1 Swiss-port # Q9C0C7 Human Activating molecule in BECN1-regulated autophagy protein 1 |
|---|---|
| Gene Symbol | AMBRA1 |
| Gene Full Name | autophagy/beclin-1 regulator 1 |
| Function | Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). [UniProt] |
| Cellular Localization | Autophagosome. Note: Localizes also to discrete punctae along the ciliary axoneme. [UniProt] |
| Calculated MW | 143 kDa |
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