ARG45604

anti-AMPD1 antibody

anti-AMPD1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes AMPD1
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name AMPD1
Antigen Species Human
Immunogen Recombinant protein containing to human AMPD1.
Conjugation Un-conjugated
Alternate Names AMPD1; Adenosine Monophosphate Deaminase 1; Myoadenylate Deaminase; MADA; MAD; Adenosine Monophosphate Deaminase 1 (Isoform M); Skeletal Muscle AMPD; AMP Deaminase 1; EC 3.5.4.6; Adenosine Monophosphate Deaminase-1 (Muscle); AMP Deaminase Isoform M; AMPD Isoform M; MMDD; AMPD

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 103425 Mouse NCLN

GeneID: 314648 Rat NCLN

GeneID: 56926 Human NCLN

Gene Symbol AMPD1
Gene Full Name Adenosine Monophosphate Deaminase 1
Background Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Function AMP deaminase plays a critical role in energy metabolism. [UniProt]
Cellular Localization Cytosol. [UniProt]
Calculated MW 63 kDa
PTM Phosphoprotein. [UniProt]

Images (5) Click the Picture to Zoom In

  • ARG45604 anti-AMPD1 antibody IHC-P image

    Immunohistochemistry: Human breast cancer stained with ARG45604 anti-AMPD1 antibody at 2 μg/ml dilution.

  • ARG45604 anti-AMPD1 antibody WB image

    Western blot: MCF-7 stained with ARG45604 anti-AMPD1 antibody at 0.5 μg/ml dilution.

  • ARG45604 anti-AMPD1 antibody FACS image

    Flow Cytometry: U251 stained with ARG45604 anti-AMPD1 antibody at 1 µg/10^6 cells dilution.

  • ARG45604 anti-AMPD1 antibody WB image

    Western blot: Rat heart stained with ARG45604 anti-AMPD1 antibody at 0.5 μg/ml dilution.

  • ARG45604 anti-AMPD1 antibody WB image

    Western blot: Mouse skeletal muscle stained with ARG45604 anti-AMPD1 antibody at 0.5 μg/ml dilution.