ARG46013
anti-APOBEC3G antibody
anti-APOBEC3G antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes APOBEC3G |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | APOBEC3G |
| Antigen Species | Human |
| Immunogen | A 15 amino acid synthetic peptide within the first 50 amino acids of human APOBEC3G. |
| Conjugation | Un-conjugated |
| Alternate Names | APOBEC3G; ARP-9; APOBEC-related cytidine deaminase; Deoxycytidine deaminase; APOBEC-related protein; dJ494G10.1; DNA dC->dU-editing enzyme APOBEC-3G; CEM-15; CEM15; ARCD; ARP9; APOBEC-related protein 9; EC 3.5.4.-; A3G; bK150C2.7; MDS019 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9HC16 Human DNA dC->dU-editing enzyme APOBEC-3G |
|---|---|
| Gene Symbol | APOBEC3G |
| Gene Full Name | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| Background | This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Jul 2008] |
| Calculated MW | 46 kDa |
| PTM | Ubiquitinated in the presence of HIV-1 VIF. Association with VIF targets the protein for proteolysis by the ubiquitin-dependent proteasome pathway. Phosphorylation at Thr-32 reduces its binding to HIV-1 VIF and subsequent ubiquitination and degradation thus promoting its antiviral activity. |
Images (2) Click the Picture to Zoom In
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ARG46013 anti-APOBEC3G antibody IHC-P image
Immunohistochemistry: Human spleen stained with ARG46013 anti-APOBEC3G antibody.
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ARG46013 anti-APOBEC3G antibody WB image
Western blot: Caco-2 stained with ARG46013 anti-APOBEC3G antibody.
