ARG45715
anti-Agpat2 antibody
anti-Agpat2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Agpat2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Agpat2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Agpat2. |
| Conjugation | Un-conjugated |
| Alternate Names | AGPAT2; 1-Acylglycerol-3-Phosphate O-Acyltransferase 2; LPAAT-Beta; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Beta; LPLAT2; 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta); Lysophosphatidic Acid Acyltransferase-Beta; Lysophospholipid Acyltransferase 2; 1-AGP Acyltransferase 2; BSCL; Berardinelli-Seip Congenital Lipodystrophy; Lysophosphatidic Acid Acyltransferase Beta; Testicular Tissue Protein Li 143; EC 2.3.1.51; 1-AGPAT 2; 1-AGPAT2; BSCL1; LPAAB |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 33 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O15120 Human 1-acyl-sn-glycerol-3-phosphate acyltransferase beta Swiss-port # Q8K3K7 Mouse 1-acyl-sn-glycerol-3-phosphate acyltransferase beta |
|---|---|
| Gene Symbol | AGPAT2 |
| Gene Full Name | 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 |
| Background | This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 31 kDa |
Images (6) Click the Picture to Zoom In
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ARG45715 anti-Agpat2 antibody IHC-P image
Immunohistochemistry: Human gall bladder adenosquamous carcinoma stained with ARG45715 anti-Agpat2 antibody at 2 μg/ml dilution.
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ARG45715 anti-Agpat2 antibody WB image
Western blot: HEK293 stained with ARG45715 anti-Agpat2 antibody at 0.5 μg/ml dilution.
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ARG45715 anti-Agpat2 antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG45715 anti-Agpat2 antibody at 2 μg/ml dilution.
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ARG45715 anti-Agpat2 antibody WB image
Western blot: Rat liver stained with ARG45715 anti-Agpat2 antibody at 0.5 μg/ml dilution.
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ARG45715 anti-Agpat2 antibody IHC-P image
Immunohistochemistry: Mouse intestines stained with ARG45715 anti-Agpat2 antibody at 2 μg/ml dilution.
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ARG45715 anti-Agpat2 antibody WB image
Western blot: Mouse liver stained with ARG45715 anti-Agpat2 antibody at 0.5 μg/ml dilution.
