ARG10470

anti-Albumin antibody [15C7]

anti-Albumin antibody [15C7] for ELISA,Western blot and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [15C7] recognizes Albumin
Tested Reactivity Hu
Tested Application ELISA, WB
Host Mouse
Clonality Monoclonal
Clone 15C7
Isotype IgG2b
Target Name Albumin
Antigen Species Human
Immunogen human serum albumin
Conjugation Un-conjugated
Full Name albumin
Alternate Names FDAH; PRO0883; PRO1341; Serum albumin; ANALBA; PRO0903

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A affinity purified.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Concentration 1.0-2.0 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 213 Human ALB

Swiss-port # P02768 Human Serum albumin

Gene Symbol ALB
Gene Full Name albumin
Background Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
Function Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. [UniProt]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Signaling Transduction antibody
PTM Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylated by FAM20C in the extracellular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

Clone References

Fast fixing and comprehensive identification to help improve real-time ligands discovery based on formaldehyde crosslinking, immunoprecipitation and SDS-PAGE separation.

ICC/IF / Human

Zhu L et al.
Proteome Sci.,  (2014)

publication_link

 

hr_line

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface.

Salvati A et al.
Nat Nanotechnol.,  (2013)

publication_link

 

hr_line

Transferrin coated nanoparticles: study of the bionano interface in human plasma.

Dot / 

Pitek AS et al.
PLoS One.,  (2012)

publication_link

 

hr_line

Brain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease.

WB / Human

Yin X et al.
Am J Pathol.,  (2010)

publication_link

 

hr_line

Expedited growth factor-mediated specification of human embryonic stem cells toward the hepatic lineage.

ICC/IF / Human

Moore RN et al.
Stem Cell Res.,  (2009)

publication_link

 

hr_line