ARG20583

anti-Aquaporin 1 antibody

anti-Aquaporin 1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description

Rabbit Polyclonal antibody recognizes Aquaporin 1

Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Aquaporin 1
Antigen Species Rat
Immunogen Synthetic peptide around the N-terminus of Rat Aquaporin 1. (N-MASEFKKKLF)
Conjugation Un-conjugated
Full Name aquaporin 1
Alternate Names AQP-1; Aquaporin-1; Water channel protein for red blood cells and kidney proximal tubule; CHIP28; Aquaporin-CHIP; CO; AQP-CHIP; Urine water channel

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:400
IHC-P1:200
WB1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 28.5 kDa (unmodified); 35 - 50 kDa (glycosylated)

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C . Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 11826 Mouse AQP1

GeneID: 25240 Rat AQP1

GeneID: 358 Human AQP1

Gene Symbol Aqp1
Gene Full Name aquaporin 1
Background Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Function Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG20583 anti-Aquaporin 1 antibody ICC/IF image

    Immunofluorescence: Rat kidney tissue stained with ARG20583 anti-Aquaporin 1 antibody at 1:200 dilution.  DAPI merge.

  • ARG20583 anti-Aquaporin 1 antibody WB image

    Western blot: Rat kidney tissue stained with ARG20583 anti-Aquaporin 1 antibody at 1:2000 dilution. Showing glyco and non-glycosylated bands.