anti-Aquaporin 3 antibody

anti-Aquaporin 3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,IHC-Frozen sections,Immunoprecipitation,Western blot and Human,Mouse,Rat

publication_link Publication2


Product Description Rabbit Polyclonal antibody recognizes Aquaporin 3
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-Fr, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Aquaporin 3
Antigen Species Human
Immunogen Synthetic peptide around the C-terminus of Human Aquaporin 3. (EENVKLAHVKHKEQI)
Conjugation Un-conjugated
Full Name aquaporin 3 (Gill blood group)
Alternate Names Aquaporin-3; GIL; Aquaglyceroporin-3; AQP-3

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF0.5 - 1 µg/ml
IHC-Fr0.5 - 1 µg/ml
IHC-P0.5 - 1 µg/ml
IP5 - 10 µg/ml
WB0.5 - 1 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 32 kDa


Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.025% Sodium azide and 2.5% BSA.
Preservative 0.025% Sodium azide
Stabilizer 2.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database links

GeneID: 11828 Mouse AQP3

GeneID: 360 Human AQP3

GeneID: 65133 Rat AQP3

Gene Symbol AQP3
Gene Full Name aquaporin 3 (Gill blood group)
Background This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. [provided by RefSeq, Aug 2011]
Function Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity). [UniProt]

Images (4) Click the Picture to Zoom In

  • ARG10648 anti-Aquaporin 3 antibody ICC/IF image

    Immunocytochemistry: HeLa cells stained with ARG10648 anti-Aquaporin 3 antibody.

  • ARG10648 anti-Aquaporin 3 antibody WB image

    Western blot: 1) Rat kidney, 2) Rat lung, 3) Mouse kidney, 4) MDA-MB-453, a human breast cancer line, and 5) SMMC-7221, a human hepatocarcinoma cell line. Lysates stained with ARG10648 anti-Aquaporin 3 antibody.

  • ARG10648 anti-Aquaporin 3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG10648 anti-Aquaporin 3 antibody.

  • ARG10648 anti-Aquaporin 3 antibody IHC-Fr image

    Immunohistochemistry: Frozen section of Rat kidney tissue stained with ARG10648 anti-Aquaporin 3 antibody.

Specific References

Predicting the effects of radiotherapy based on diffusion kurtosis imaging in a xenograft mouse model of esophageal carcinoma.

WB / Human

An-Du Zhang et al.
Experimental and Therapeutic Medicine.,  (2021)




Improvement of Skin Penetration, Antipollutant Activity and Skin Hydration of 7,3',4'-Trihydroxyisoflavone Cyclodextrin Inclusion Complex.

WB / Human

Huang Pao-Hsien et al.
Pharmaceutics.,  (2019)