ARG46020
anti-Arylsulfatase B antibody
anti-Arylsulfatase B antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Arylsulfatase B |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Arylsulfatase B |
| Antigen Species | Human |
| Immunogen | A 16 amino acid synthetic peptide within aa. 460 - 510 of human Arylsulfatase B. |
| Conjugation | Un-conjugated |
| Alternate Names | ARSB; N-acetylgalactosamine-4-sulfatase; EC 3.1.6.12; MPS6; ASB; G4S; Arylsulfatase B |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 57 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ARSB |
| Gene Full Name | arylsulfatase B |
| Background | Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Calculated MW | 59 kDa |
| PTM | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD). |
Images (2) Click the Picture to Zoom In
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ARG46020 anti-Arylsulfatase B antibody IHC-P image
Immunohistochemistry: Human lung stained with ARG46020 anti-Arylsulfatase B antibody.
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ARG46020 anti-Arylsulfatase B antibody WB image
Western blot: Mouse lung stained with ARG46020 anti-Arylsulfatase B antibody.
