ARG45498
anti-BCAT1 antibody
anti-BCAT1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BCAT1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BCAT1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human BCAT1. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 2.6.1.42; c; BCT1; ECA39; PP18; Branched-chain-amino-acid aminotransferase, cytosolic; PNAS121; MECA39; Protein ECA39; BCAT; BCATC |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 43 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BCAT1 |
| Gene Full Name | branched chain amino-acid transaminase 1, cytosolic |
| Background | This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 43 kDa |
| PTM | Acetylation. [UniProt] |
Images (7) Click the Picture to Zoom In
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ARG45498 anti-BCAT1 antibody IHC-P image
Immunohistochemistry: Human lymphoma stained with ARG45498 anti-BCAT1 antibody at 2 μg/ml dilution.
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ARG45498 anti-BCAT1 antibody WB image
Western blot: Hela stained with ARG45498 anti-BCAT1 antibody at 0.5 μg/ml dilution.
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ARG45498 anti-BCAT1 antibody FACS image
Flow Cytometry: U937 stained with ARG45498 anti-BCAT1 antibody at 1 µg/10^6 cells dilution.
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ARG45498 anti-BCAT1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45498 anti-BCAT1 antibody at 2 μg/ml dilution.
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ARG45498 anti-BCAT1 antibody WB image
Western blot: Rat kidney stained with ARG45498 anti-BCAT1 antibody at 0.5 μg/ml dilution.
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ARG45498 anti-BCAT1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45498 anti-BCAT1 antibody at 2 μg/ml dilution.
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ARG45498 anti-BCAT1 antibody WB image
Western blot: Mouse kidney stained with ARG45498 anti-BCAT1 antibody at 0.5 μg/ml dilution.
