ARG46209
anti-BIRC8 antibody
anti-BIRC8 antibody for Western blot,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BIRC8 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BIRC8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide near the amino terminus of human BIRC8. |
| Conjugation | Un-conjugated |
| Alternate Names | BIRC8; ILP-2; ILP2; Baculoviral IAP repeat-containing protein 8; IAP-like protein 2; hILP2; Inhibitor of apoptosis-like protein 2; Testis-specific inhibitor of apoptosis |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96P09 Human Baculoviral IAP repeat-containing protein 8 |
|---|---|
| Gene Symbol | BIRC8 |
| Gene Full Name | baculoviral IAP repeat containing 8 |
| Background | ILP-2 (for IAP-like protein-2) is a novel member of in the IAP (Inhibitor of Apoptosis) protein family. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibit apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. |
| Function | Protects against apoptosis mediated by BAX. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46209 anti-BIRC8 antibody ICC/IF image
Immunofluorescence: HepG2 stained with ARG46209 anti-BIRC8 antibody.
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ARG46209 anti-BIRC8 antibody WB image
Western blot: HepG2 stained with ARG46209 anti-BIRC8 antibody.
