ARG44564
anti-BMP15 antibody
anti-BMP15 antibody for ICC/IF,Western blot and Human,Mouse
Premature ovarian failure. [UniProt]
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BMP15 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BMP15 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human BMP15 (a.a. 30-80). |
| Conjugation | Un-conjugated |
| Alternate Names | BMP15; Bone Morphogenetic Protein 15; GDF9B; Growth/Differentiation Factor 9B; BMP-15; GDF-9B; ODG2; POF4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography using the peptide immobilized |
| Buffer | PBS with 0.02% sodium azide. |
| Preservative | 0.02% sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BMP15 |
| Gene Full Name | Bone Morphogenetic Protein 15 |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016] |
| Function | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Research Area | Premature ovarian failure. [UniProt] |
| Calculated MW | 45 kDa |
| PTM | Secreted. [UniProt] |
