ARG46893
anti-BROX antibody
anti-BROX antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes BROX |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | BROX |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human BROX. |
| Conjugation | Un-conjugated |
| Alternate Names | BROX; BRO1 domain-containing protein BROX; BROFTI; C1orf58; BRO1 domain- and CAAX motif-containing protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5VW32 Human BRO1 domain-containing protein BROX |
|---|---|
| Gene Symbol | BROX |
| Gene Full Name | BRO1 domain-containing protein BROX |
| Background | Involved in mitotic nuclear membrane reassembly. Located in nuclear envelope. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane. [UniProt] |
| Cellular Localization | Nucleus; Membrane. [UniProt] |
| Calculated MW | 46 kDa |
| PTM | Acetylation; Lipoprotein; Methylation. [UniProt] |
