ARG47090
anti-C3orf37 antibody
anti-C3orf37 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes C3orf37 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | C3orf37 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human C3orf37. |
| Conjugation | Un-conjugated |
| Alternate Names | HMCES; Abasic site processing protein HMCES; C3orf37; DC12; SRAPD1; Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; ES cell-specific 5hmC-binding protein; Peptidase HMCES; SRAP domain-containing protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.09% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96FZ2 Human Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein |
|---|---|
| Gene Symbol | HMCES |
| Gene Full Name | 5-hydroxymethylcytosine binding, ES cell specific |
| Background | Enables DNA-(abasic site) binding activity; protein-DNA covalent cross-linking activity; and single-stranded DNA binding activity. Involved in interstrand cross-link repair; protein-DNA covalent cross-linking repair; and somatic hypermutation of immunoglobulin genes. Is active in replication fork. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. [UniProt] |
| Cellular Localization | Chromosome. [UniProt] |
| Calculated MW | 41 kDa |
| PTM | Autocatalytic cleavage; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
