anti-CA19-9 antibody [121SLE]

anti-CA19-9 antibody [121SLE] for ELISA,IHC-Formalin-fixed paraffin-embedded sections and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody


Product Description

Mouse Monoclonal antibody [121SLE] recognizes CA19-9

Tested Reactivity Hu
Tested Application ELISA, IHC-P
Specificity The clone 121SLE recognizes Sialyl Lewis a containing glycolipids (CA19-9).
Host Mouse
Clonality Monoclonal
Clone 121SLE
Isotype IgM
Target Name CA19-9
Immunogen Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.
Conjugation Un-conjugated
Alternate Names SIAT7F; SIAT7-F; ST6GALNACV; CA19-9

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P10 µg/ml
Application Note IHC-P: Positive control:colorectal adenocarcinoma Application note:heat mediated antigen retrieval (sodium citrate); mAb incubation 1 hour / RT; detection DAB
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purified from ascites by precipitation methods and size-exclusion chromatography.
Purity > 95% (by SDS-PAGE)
Buffer TBS (pH 8.0) and 15 mM Sodium azide
Preservative 15 mM Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 30815 Human ST6GALNAC6

Swiss-port # Q969X2 Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Gene Symbol ST6GALNAC6
Gene Full Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Background ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008]
Function Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)). [UniProt]
Highlight Related products:
CA19-9 antibodies; CA19-9 ELISA Kits; Anti-Mouse IgM secondary antibodies;
Related news:
More than a biomarker, CA19-9 is a therapeutic target of pancreatic cancer
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody
Calculated MW 38 kDa

Images (2) Click the Picture to Zoom In

  • ARG63094 anti-CA19-9 antibody [121SLE] IHC-P image

    Immunohistochemistry: Paraffin-embedded Human pancreas tissue stained with ARG63094 anti-CA19-9 antibody [121SLE] at 10 µg/ml dilution.

  • ARG63094 anti-Sialyl Lewis a antibody [121SLE] IHC-P image

    Immunohistochemistry: Colorectal adenocarcinoma section stained with ARG63094 anti-Sialyl Lewis a antibody [121SLE].