ARG45817
anti-CACYBP antibody
anti-CACYBP antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CACYBP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CACYBP |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to N-terminal region of human CACYBP. |
| Conjugation | Un-conjugated |
| Alternate Names | calcyclin binding protein; S100A6-binding protein; SIP; S100A6BP; GIG5; hCacyBP; CacyBP; Siah-interacting protein; Calcyclin-binding protein; PNAS-107 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| Observed Size | 26 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 5% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CACYBP |
| Gene Full Name | calcyclin binding protein |
| Background | The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 26 kDa |
| PTM | Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations. [UniProt] |
Images (7) Click the Picture to Zoom In
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ARG45817 anti-CACYBP antibody IHC-P image
Immunohistochemistry: Human intestinal cancer stained with ARG45817 anti-CACYBP antibody at 1 μg/ml dilution.
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ARG45817 anti-CACYBP antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45817 anti-CACYBP antibody at 1 μg/ml dilution.
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ARG45817 anti-CACYBP antibody WB image
Western blot: MCF-7 and RT4 stained with ARG45817 anti-CACYBP antibody at 0.5 μg/ml dilution.
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ARG45817 anti-CACYBP antibody IP image
Immunoprecipitation: U251 lysate immunoprecipitated with 2 μg ARG45817 anti-CACYBP antibody.
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ARG45817 anti-CACYBP antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45817 anti-CACYBP antibody at 1 μg/ml dilution.
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ARG45817 anti-CACYBP antibody WB image
Western blot: Rat liver stained with ARG45817 anti-CACYBP antibody at 0.5 μg/ml dilution.
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ARG45817 anti-CACYBP antibody WB image
Western blot: Mouse liver stained with ARG45817 anti-CACYBP antibody at 0.5 μg/ml dilution.
