ARG46061
anti-CARD8 antibody
anti-CARD8 antibody for Western blot,ICC/IF and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CARD8 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CARD8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide near the C-terminus of human CARD8. |
| Conjugation | Un-conjugated |
| Alternate Names | CARD8; TUCAN; Apoptotic protein NDPP1; CARD-inhibitor of NF-kappa-B-activating ligand; NDPP1; DACAR; CARDINAL; Tumor up-regulated CARD-containing antagonist of CASP9; Caspase recruitment domain-containing protein 8; DAKAR; NDPP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 47 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y2G2 Human Caspase recruitment domain-containing protein 8 |
|---|---|
| Gene Symbol | CARD8 |
| Gene Full Name | caspase recruitment domain family, member 8 |
| Background | TUCAN (Tumor Up-regulated Card-containing Antagonist of Caspase-Nine) is a CARD (Caspase-Associated Recruitment Domains) containing protein that binds and suppresses activation of pro-Caspase-9 and found to be overexpressed in some types of cancers. TUCAN binds specifically to pro-caspase-9 and interferes with its interaction with Apaf-1, thereby suppressing apoptosis signaling in the mitochondrial/cytochrome c pathway. |
| Calculated MW | 47 kDa |
Images (2) Click the Picture to Zoom In
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ARG46061 anti-CARD8 antibody ICC/IF image
Immunofluorescence: K562 stained with ARG46061 anti-CARD8 antibody.
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ARG46061 anti-CARD8 antibody WB image
Western blot: Human lung stained with ARG46061 anti-CARD8 antibody.
