ARG46933
anti-CCDC62 antibody
anti-CCDC62 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes CCDC62 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | CCDC62 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CCDC62. |
| Conjugation | Un-conjugated |
| Alternate Names | CCDC62; Coiled-coil domain-containing protein 62; Protein TSP-NY; Protein aaa |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6P9F0 Human Coiled-coil domain-containing protein 62 |
|---|---|
| Gene Symbol | CCDC62 |
| Gene Full Name | Coiled-coil domain-containing protein 62 |
| Background | Enables nuclear estrogen receptor binding activity and transcription coactivator activity. Involved in several processes, including cellular response to estradiol stimulus; estrogen receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in acrosomal vesicle and nucleoplasm. Implicated in spermatogenic failure 67. [provided by Alliance of Genome Resources, Jun 2026] |
| Function | Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Also modulates progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. Required for normal spermiogenesis. It probably plays a role in acrosome formation (By similarity). [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Cytoplasmic vesicle. [UniProt] |
| Calculated MW | 78 kDa |
