anti-CD103 / Integrin alpha E antibody [Ber-ACT8] (PE)

anti-CD103 / Integrin alpha E antibody [Ber-ACT8] (PE) for Flow cytometry and Human,Primates

Developmental Biology antibody; Immune System antibody; Signaling Transduction antibody


Product Description

PE-conjugated Mouse Monoclonal antibody [Ber-ACT8] recognizes CD103 / Integrin alpha E

Tested Reactivity Hu, NHuPrm
Tested Application FACS
Specificity The clone Ber-ACT8 recognizes CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes.
HLDA V; WS Code A067
Host Mouse
Clonality Monoclonal
Clone Ber-ACT8
Isotype IgG1
Target Name CD103 / Integrin alpha E
Antigen Species Human
Immunogen HTLV-1 induced human T cell line MAPS16
Conjugation PE
Alternate Names CD103; HUMINAE; Integrin alpha-E; Mucosal lymphocyte 1 antigen; CD antigen CD103; HML-1 antigen; Integrin alpha-IEL

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3682 Human ITGAE

Swiss-port # P38570 Human Integrin alpha-E

Gene Symbol ITGAE
Gene Full Name integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Background CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activation.
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. [UniProt]
Research Area Developmental Biology antibody; Immune System antibody; Signaling Transduction antibody
Calculated MW 130 kDa

Images (1) Click the Picture to Zoom In

  • ARG54227 anti-CD103 / Integrin alpha E antibody [Ber-ACT8] (PE) FACS image

    Flow Cytometry: PHA-activated PBMC stained with ARG54227 anti-CD103 / Integrin alpha E antibody [Ber-ACT8] (PE).