anti-CD11a / LFA1 alpha antibody [38] (PE)

anti-CD11a / LFA1 alpha antibody [38] (PE) for Flow cytometry,IHC-Frozen sections,Blocking,ELISA and Human


Product Description PE-conjugated Mouse Monoclonal antibody [38] recognizes CD11a / LFA1 alpha
Tested Reactivity Hu
Tested Application BL, ELISA, FACS, IHC-Fr
Specificity Human CD11a.
Host Mouse
Clonality Monoclonal
Clone 38
Isotype IgG2a, kappa
Target Name CD11a / LFA1 alpha
Antigen Species Human
Immunogen Fibronectin purified monocytes
Conjugation PE
Alternate Names Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA1A; LFA-1A; Integrin alpha-L; CD11A; Leukocyte function-associated molecule 1 alpha chain; LFA-1; CD11 antigen-like family member A; CD antigen CD11a

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3683 Human ITGAL

Swiss-port # P20701 Human Integrin alpha-L

Gene Symbol ITGAL
Gene Full Name integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Background ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. [UniProt]
Calculated MW 129 kDa
PTM In resting T-cells, up to 40% of surface ITGAL is constitutively phosphorylated. Phosphorylation causes conformational changes needed for ligand binding and is necessary for activation by some physiological agents.

Images (1) Click the Picture to Zoom In

  • ARG21253 anti-CD11a / LFA1 alpha antibody [38] (PE) FACS image

    Flow Cytometry: Human peripheral blood lymphocytes stained with ARG21253 anti-CD11a / LFA1 alpha antibody [38] (PE).