anti-CD11c antibody

anti-CD11c antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

publication_link Publication3


Product Description Rabbit Polyclonal antibody recognizes CD11c
Tested Reactivity Hu, Ms
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD11c
Antigen Species Human
Immunogen Synthetic peptide derived from Human CD11c.
Conjugation Un-conjugated
Alternate Names CD antigen CD11c; Leu M5; CD11C; SLEB6; Integrin alpha-X; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11 antigen-like family member C

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 150 kDa


Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 16411 Mouse ITGAX

GeneID: 3687 Human ITGAX

Swiss-port # P20702 Human Integrin alpha-X

Swiss-port # Q9QXH4 Mouse Integrin alpha-X

Gene Symbol ITGAX
Gene Full Name integrin, alpha X (complement component 3 receptor 4 subunit)
Background This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Function Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 128 kDa

Images (2) Click the Picture to Zoom In

  • ARG59698 anti-CD11c antibody WB image

    Western blot: THP-1 cell lysate treated with TPA and stained with ARG59698 anti-CD11c antibody.

  • ARG59698 anti-CD11c antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human spleen stained with ARG59698 anti-CD11c antibody.

Specific References

Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice

IHC-P / Mouse

Yaxin Fu et al.
Int J Mol Sci,  (2022)




Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.

IHC-P / Mouse

Quan Liu et al.
Front Pharmacol.,  (2021)




Abrogation of Toll like receptor 4 (TLR4) mitigates obesity-induced oxidative stress, proinflammation, and insulin resistance through metabolic reprogramming of mitochondria in adipose tissue.

IHC-P / Mouse

Lin Hung-Yu et al.
Antioxid Redox Signal.,  (2020)