ARG46737
anti-CD11c antibody [N418] (Violet 450)
anti-CD11c antibody [N418] (Violet 450) for Flow cytometry and Mouse
Overview
| Product Description | Hamster Monoclonal antibody [N418] recognizes CD11c |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS |
| Host | Hamster |
| Clonality | Monoclonal |
| Clone | N418 |
| Isotype | IgG |
| Target Name | CD11c |
| Antigen Species | Mouse |
| Immunogen | Mouse spleen dendritic cells. |
| Conjugation | Violet 450 |
| Alternate Names | CD antigen CD11c; Leu M5; CD11C; SLEB6; Integrin alpha-X; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11 antigen-like family member C |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% sodium azide, and 0.2% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.2% BSA |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ITGAX |
| Gene Full Name | integrin, alpha X (complement component 3 receptor 4 subunit) |
| Background | This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [UniProt] |
| Calculated MW | 128 kDa |
Images (1) Click the Picture to Zoom In
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AARG46737 anti-CD11c antibody [N418] (Violet 450) FACS image
Flow Cytometry: C57BL/6J stained with ARG46737 anti-CD11c antibody [N418] (Violet 450).
