anti-CD138 / Syndecan 1 antibody [SQab1741]

anti-CD138 / Syndecan 1 antibody [SQab1741] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human


Product Description Recombinant Rabbit Monoclonal antibody [SQab1741] recognizes CD138 / Syndecan 1
Tested Reactivity Hu
Tested Application FACS, IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab1741
Isotype IgG
Target Name CD138 / Syndecan 1
Antigen Species Human
Immunogen Synthetic peptide around aa. 200-300 of Human CD138.
Conjugation Un-conjugated
Alternate Names CD antigen CD138; syndecan; CD138; SDC; Syndecan-1; SYND1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:25 - 1:100
IHC-P1:100 - 1:200
Application Note IHC-P: Antigen Retrieval: Boil tissue section in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 6382 Human SDC1

Swiss-port # P18827 Human Syndecan-1

Gene Symbol SDC1
Gene Full Name syndecan 1
Background The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
Function Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. [UniProt]
Highlight Related products:
CD138 antibodies; CD138 ELISA Kits; Anti-Rabbit IgG secondary antibodies;
Related news:
Cancer Pathology Markers (SQ clones)
Calculated MW 32 kDa
PTM Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG66252 anti-CD138 / Syndecan 1 antibody [SQab1741] FACS image

    Flow Cytometry: Raji cells were fixed with 4% paraformaldehyde for 10 min. The cells were then stained with ARG66252 anti-CD138 / Syndecan 1 antibody [SQab1741] (red) at 1:100 dilution in 1x PBS/1% BSA for 30 min at room temperature, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (Black) was used as a control.

  • ARG66252 anti-CD138 / Syndecan 1 antibody [SQab1741] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human Liver tissue stained with ARG66252 anti-CD138 / Syndecan 1 antibody [SQab1741] at 1:200. Antigen Retrieval: Boil tissue section in Tris/EDTA buffer (pH 9.0).