ARG54668

anti-CD150 / SLAM antibody

anti-CD150 / SLAM antibody for ELISA,Immunohistochemistry,Western blot,ICC/IF and Human,Mouse,Rat

Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes CD150 / SLAM
Tested Reactivity Hu, Ms, Rat
Tested Application ELISA, ICC/IF, IHC, WB
Specificity Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD150 / SLAM
Immunogen Synthetic peptide (15 aa) within aa. 30-80 of Human SLAMF1.
Conjugation Un-conjugated
Alternate Names Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-Dependent
ICC/IF20 μg/mL
IHC5 μg/mL
WB1 μg/mL
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat Colon Lysate

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 27218 Mouse SLAMF1

GeneID: 6504 Human SLAMF1

Swiss-port # Q13291 Human Signaling lymphocytic activation molecule

Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule

Gene Symbol SLAMF1
Gene Full Name signaling lymphocytic activation molecule family member 1
Background SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP). |
Research Area Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody
Calculated MW 37 kDa
PTM Phosphorylated on tyrosine residues by FYN.

Images (3) Click the Picture to Zoom In

  • ARG54668 anti-CD150 / SLAM antibody ICC/IF image

    Immunofluorescence: Human colon tissue stained with ARG54668 anti-CD150 / SLAM antibody at 20 μg/ml.

  • ARG54668 anti-CD150 / SLAM antibody IHC image

    Immunohistochemistry: Human colon tissue stained with ARG54668 anti-CD150 / SLAM antibody at 5 μg/ml.

  • ARG54668 anti-CD150 / SLAM antibody WB image

    Western blot: Rat colon tissue lysate stained with ARG54668 anti-CD150 / SLAM antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.