anti-CD1a antibody [HI149] (APC)

anti-CD1a antibody [HI149] (APC) for Flow cytometry and Human

Immune System antibody


Product Description APC-conjugated Mouse Monoclonal antibody [HI149] recognizes CD1a
Tested Reactivity Hu
Tested Application FACS
Specificity The clone HI149 reacts with CD1a (T6), a 49 kDa polypeptide associated with beta2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas.
does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.
HLDA V; WS Code CD01.01
Host Mouse
Clonality Monoclonal
Clone HI149
Isotype IgG1
Target Name CD1a
Antigen Species Human
Immunogen Human thymocytes
Conjugation APC
Alternate Names R4; FCB6; CD antigen CD1a; T6; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; T-cell surface glycoprotein CD1a; CD1; HTA1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 909 Human CD1A

Swiss-port # P06126 Human T-cell surface glycoprotein CD1a

Gene Symbol CD1A
Gene Full Name CD1a molecule
Background CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.
Function Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. [UniProt]
Highlight Related products:
CD1a antibodies; Anti-Mouse IgG secondary antibodies;
Related news:
Detecting exosomal HMGB1 for ICD research
Research Area Immune System antibody
Calculated MW 37 kDa

Images (1) Click the Picture to Zoom In

  • ARG53785 anti-CD1a antibody [HI149] (APC) FACS image

    Flow Cytometry: MOLT-4 cells (partially positive, red) and SP2 cells (negative, blue) stained with ARG53785 anti-CD1a antibody [HI149] (APC).