ARG20811

anti-CD2 antibody [12-15]

anti-CD2 antibody [12-15] for Flow cytometry,Immunoprecipitation,Blocking,Purification and Mouse

Overview

Product Description Rat Monoclonal antibody [12-15] recognizes CD2
Tested Reactivity Ms
Tested Application BL, FACS, IP, Puri
Specificity Mouse CD2.
Host Rat
Clonality Monoclonal
Clone 12-15
Isotype IgG1, kappa
Target Name CD2
Antigen Species Mouse
Immunogen Crude plasma membranes of ESb cells
Conjugation Un-conjugated
Full Name CD2 antigen
Alternate Names T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
FACSAssay-dependent
IPAssay-dependent
PuriAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 39 kDa

Properties

Form Liquid
Buffer BBS (pH 8.2)
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12481 Mouse CD2

Swiss-port # P08920 Mouse T-cell surface antigen CD2

Gene Symbol CD2
Gene Full Name CD2 antigen
Background CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
Function CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt]