anti-CD200 antibody [OX-104] (APC)

anti-CD200 antibody [OX-104] (APC) for Flow cytometry and Human

Cell Biology and Cellular Response antibody; Immune System antibody


Product Description APC-conjugated Mouse Monoclonal antibody [OX-104] recognizes CD200
Tested Reactivity Hu
Tested Application FACS
Specificity The clone OX-104 recognizes CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.
Host Mouse
Clonality Monoclonal
Clone OX-104
Isotype IgG1
Target Name CD200
Antigen Species Human
Immunogen Human CD200
Conjugation APC
Alternate Names OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 4345 Human CD200

Swiss-port # P41217 Human OX-2 membrane glycoprotein

Gene Symbol CD200
Gene Full Name CD200 molecule
Background CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
Function Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Immune System antibody
Calculated MW 31 kDa

Images (1) Click the Picture to Zoom In

  • ARG54292 anti-CD200 antibody [OX-104] (APC) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG54292 anti-CD200 antibody [OX-104] (APC) and anti-CD3 antibody (PE).

Clone References

Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.

Adhikary G et al.
PLoS One.,  (2013)




Activation of protease-activated receptor 2 induces VEGF independently of HIF-1.

FACS / Human

Rasmussen JG et al.
PLoS One.,  (2012)




Differential expression of stem-cell-associated markers in human hair follicle epithelial cells.

ICC/IF / Human

Inoue K et al.
Lab Invest.,  (2009)