anti-CD21 antibody [LT21] (PE)

anti-CD21 antibody [LT21] (PE) for Flow cytometry and Human,Bovine,Dog,Pig

Immune System antibody


Product Description

PE-conjugated Mouse Monoclonal antibody [LT21] recognizes CD21

Tested Reactivity Hu, Bov, Dog, Pig
Tested Application FACS
Specificity The clone LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
HLDA VI; WS Code B CD21.1
Host Mouse
Clonality Monoclonal
Clone LT21
Isotype IgG1
Target Name CD21
Antigen Species Human
Immunogen IM9 human B-lymphoblastoid cell line
Conjugation PE
Alternate Names Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACS20 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 1380 Human CR2

Swiss-port # P20023 Human Complement receptor type 2

Gene Symbol CR2
Gene Full Name complement component (3d/Epstein Barr virus) receptor 2
Background CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Function Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt]
Research Area Immune System antibody
Calculated MW 113 kDa

Images (1) Click the Picture to Zoom In

  • ARG53791 anti-CD21 antibody [LT21] (PE) FACS image

    Flow Cytometry: Human peripheral blood leukocytes stained with ARG53791 anti-CD21 antibody [LT21] (PE).