anti-CD223 / LAG3 antibody [SQab22258]

anti-CD223 / LAG3 antibody [SQab22258] for IHC-Formalin-fixed paraffin-embedded sections and Human


Product Description Recombinant Rabbit Monoclonal antibody [SQab22258] recognizes CD223 / LAG3
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab22258
Isotype IgG
Target Name CD223 / LAG3
Antigen Species Human
Immunogen Synthetic peptide within Human LAG-3.
Conjugation Un-conjugated
Protein Full Name Lymphocyte activation gene 3 protein
Alternate Names CD antigen CD223; CD223; Protein FDC; Lymphocyte activation gene 3 protein; LAG-3

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 30 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human lymphoma tissue


Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05%BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 3902 Human LAG3

Swiss-port # P18627 Human Lymphocyte activation gene 3 protein

Gene Symbol LAG3
Gene Full Name lymphocyte-activation gene 3
Background Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
Function Involved in lymphocyte activation. Binds to HLA class-II antigens. [UniProt]
Cellular Localization Membrane, Single-pass type I membrane protein. [UniProt]
Calculated MW 57 kDa

Images (1) Click the Picture to Zoom In

  • ARG66930 anti-CD223 / LAG3 antibody [SQab22258] IHC-P image

    Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded sections of Human lymphoma tissue stained with ARG66930 anti-CD223 / LAG3 antibody [SQab22258]. Antigen Retrieval: Heat tissue section in Tris-EDTA buffer (pH 9.0).