ARG66348

anti-CD23 antibody [SQab1898]

anti-CD23 antibody [SQab1898] for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Recombinant Rabbit Monoclonal antibody [SQab1898] recognizes CD23
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab1898
Isotype IgG
Target Name CD23
Antigen Species Human
Immunogen Synthetic peptide within aa. 221-321 of Human CD23.
Conjugation Un-conjugated
Full Name Fc fragment of IgE, low affinity II, receptor for (CD23)
Alternate Names CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT for 30 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 36 kDa

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 2208 Human FCER2

Swiss-port # P06734 Human Low affinity immunoglobulin epsilon Fc receptor

Gene Symbol FCER2
Gene Full Name Fc fragment of IgE, low affinity II, receptor for (CD23)
Background The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt]
Highlight Related products:
CD23 antibodies; CD23 ELISA Kits; Anti-Rabbit IgG secondary antibodies;
Related news:
Cancer Pathology Markers (SQ clones)
PTM N- and O-glycosylated.

The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG66348 anti-CD23 antibody [SQab1898] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded tonsil tissue stained with ARG66348 anti-CD23 antibody [SQab1898]. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).