anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE)

anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE) for Flow cytometry and Human

Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody


Product Description PE-conjugated Mouse Monoclonal antibody [TRAIL-R3-02] recognizes CD263 / TRAIL R3
Tested Reactivity Hu
Tested Application FACS
Specificity The clone TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Host Mouse
Clonality Monoclonal
Clone TRAIL-R3-02
Isotype IgG1
Target Name CD263 / TRAIL R3
Immunogen TRAIL-R3 (aa 1-280) - hIgGhc fusion protein
Conjugation PE
Alternate Names Lymphocyte inhibitor of TRAIL; Antagonist decoy receptor for TRAIL/Apo-2L; TNF-related apoptosis-inducing ligand receptor 3; DCR1; TRID; CD antigen CD263; Tumor necrosis factor receptor superfamily member 10C; CD263; Decoy TRAIL receptor without death domain; LIT; Decoy receptor 1; DcR1; DCR1-TNFR; TRAIL-R3; TRAIL receptor 3; TRAILR3; TRAIL receptor without an intracellular domain

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 6 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 8794 Human TNFRSF10C

Swiss-port # O14798 Human Tumor necrosis factor receptor superfamily member 10C

Gene Symbol TNFRSF10C
Gene Full Name tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Background TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).
Function Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody
Calculated MW 27 kDa
PTM N-glycosylated and O-glycosylated.

Images (1) Click the Picture to Zoom In

  • ARG53809 anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE) FACS image

    Flow Cytometry: CD263-transfected HEK293 cells stained with ARG53809 anti-CD263 / TRAIL R3 antibody [TRAIL-R3-02] (PE).