ARG22016

anti-CD30 antibody [mCD30.1] (PE)

anti-CD30 antibody [mCD30.1] (PE) for Flow cytometry,Blocking and Mouse

Overview

Product Description PE-conjugated Hamster Monoclonal antibody [mCD30.1] recognizes CD30
Tested Reactivity Ms
Tested Application BL, FACS
Specificity Mouse CD30
Host Hamster
Clonality Monoclonal
Clone mCD30.1
Isotype IgG1
Target Name CD30
Antigen Species Mouse
Immunogen Mouse CD30-Mouse IgG1 fusion protein
Conjugation PE
Alternate Names Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30; Ki-1; Lymphocyte activation antigen CD30; CD antigen CD30; D1S166E; CD30L receptor

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
FACS< 0.2 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 21941 Mouse TNFRSF8

Swiss-port # Q60846 Mouse Tumor necrosis factor receptor superfamily member 8

Gene Symbol TNFRSF8
Gene Full Name tumor necrosis factor receptor superfamily, member 8
Background CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Function CD30 is a receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898). [UniProt]
Calculated MW 64 kDa
PTM Phosphorylated on serine and tyrosine residues.

Images (1) Click the Picture to Zoom In

  • ARG22016 anti-CD30 antibody [mCD30.1] (PE) FACS image

    Flow Cytometry: NIH/Swiss Mouse fibroblast cell line 3T3 and mCD30-Ig transfected 3T3 cells stained with ARG22016 anti-CD30 antibody [mCD30.1] (PE).