anti-CD300e antibody [UP-H2] (PE)

anti-CD300e antibody [UP-H2] (PE) for Flow cytometry and Human

Immune System antibody


Product Description PE-conjugated Mouse Monoclonal antibody [UP-H2] recognizes CD300e
Tested Reactivity Hu
Tested Application FACS
Specificity The clone UP-H2 recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Host Mouse
Clonality Monoclonal
Clone UP-H2
Isotype IgG1
Target Name CD300e
Immunogen CD300e-HA-transfected cells
Conjugation PE
Alternate Names Poly-Ig receptor 2; Immune receptor expressed on myeloid cells 2; IREM-2; CD300LE; CMRF35-A5; CD antigen CD300e; CLM2; IREM2; CMRF35-like molecule 2; PIgR2; CLM-2; Polymeric immunoglobulin receptor 2; PIgR-2; CD300 antigen-like family member E

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 342510 Human CD300E

Swiss-port # Q496F6 Human CMRF35-like molecule 2

Gene Symbol CD300E
Gene Full Name CD300e molecule
Background CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Function Probably acts as an activating receptor. [UniProt]
Research Area Immune System antibody
Calculated MW 23 kDa
PTM N-glycosylated.

Images (1) Click the Picture to Zoom In

  • ARG54304 anti-CD300e antibody [UP-H2] (PE) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG54304 anti-CD300e antibody [UP-H2] (PE).

Clone References

Molecular characterization of a novel immune receptor restricted to the monocytic lineage.

Aguilar H et al.
J Immunol.,  (2004)