anti-CD38 antibody [HIT2] (PerCP)

anti-CD38 antibody [HIT2] (PerCP) for Flow cytometry and Human

Cancer antibody; Developmental Biology antibody; Immune System antibody; Metabolism antibody; Pro-B Cell Marker antibody; Pre-B Cell Marker antibody


Product Description PerCP-conjugated Mouse Monoclonal antibody [HIT2] recognizes CD38
Tested Reactivity Hu
Tested Application FACS
Specificity The clone HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.
HLDA III; WS Code T 155
Host Mouse
Clonality Monoclonal
Clone HIT2
Isotype IgG1
Target Name CD38
Antigen Species Human
Immunogen Human thymocytes in foetus
Conjugation PerCP
Alternate Names cADPr hydrolase 1; ADPRC 1; EC; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; Cyclic ADP-ribose hydrolase 1; ADPRC1; EC; ADP-ribosyl cyclase 1; 2'-phospho-cyclic-ADP-ribose transferase; CD antigen CD38; T10; 2'-phospho-ADP-ribosyl cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 952 Human CD38

Swiss-port # P28907 Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Gene Symbol CD38
Gene Full Name CD38 molecule
Background CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.
Function Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [UniProt]
Research Area Cancer antibody; Developmental Biology antibody; Immune System antibody; Metabolism antibody; Pro-B Cell Marker antibody; Pre-B Cell Marker antibody
Calculated MW 34 kDa

Images (1) Click the Picture to Zoom In

  • ARG53839 anti-CD38 antibody [HIT2] (PerCP) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG53839 anti-CD38 antibody [HIT2] (PerCP).

Clone References

The labelling index of primitive plasma cells determines the clinical behaviour of patients with myelomatosis.

Joshua D et al.
Br J Haematol.,  (1996)