ARG67247
anti-CD3G antibody [SQab30365]
anti-CD3G antibody [SQab30365] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Monoclonal antibody [SQab30365] recognizes CD3G. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30365 |
| Isotype | IgG |
| Target Name | CD3G |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to Human CD3G. |
| Conjugation | Un-conjugated |
| Alternate Names | CD3G; CD3 Gamma Subunit Of T-Cell Receptor Complex; T-Cell Surface Glycoprotein CD3 Gamma Chain; CD3-GAMMA; CD3GAMMA; CD3g Antigen, Gamma Polypeptide (TiT3 Complex); CD3g Molecule, Gamma (CD3-TCR Complex); T-Cell Receptor T3 Gamma Chain; T3G; T-Cell Antigen Receptor Complex, Gamma Subunit Of T3; CD3g Molecule, Epsilon (CD3-TCR Complex); CD3g Molecule; CD3g Antigen; IMD17 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P09693 Human T-cell surface glycoprotein CD3 gamma chain |
|---|---|
| Gene Symbol | CD3G |
| Gene Full Name | CD3G |
| Background | The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008] |
| Function | Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| Calculated MW | 20 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG67247 anti-CD3G antibody [SQab30365] IHC-P image
Immunohistochemistry: Human Lymphoma stained with ARG67247 anti-CD3G antibody [SQab30365] at 1:100 dilution.
