anti-CD48 antibody [MEM-102] (PE)

anti-CD48 antibody [MEM-102] (PE) for Flow cytometry and Human,Primates

Immune System antibody


Product Description

PE-conjugated Mouse Monoclonal antibody [MEM-102] recognizes CD48

Tested Reactivity Hu, NHuPrm
Tested Application FACS
Specificity The clone MEM-102 reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
HLDA V; WS Code AS S014
Host Mouse
Clonality Monoclonal
Clone MEM-102
Isotype IgG1
Target Name CD48
Antigen Species Human
Immunogen Raji human Burkitt's lymphoma cell line
Conjugation PE
Alternate Names Leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen; BCM1 surface antigen; CD antigen CD48; TCT.1; BLAST1; BCM1; MEM-102; mCD48; Signaling lymphocytic activation molecule 2; BLAST; hCD48; SLAMF2; SLAM family member 2

Application Instructions

Application Suggestion
Tested Application Dilution
FACS20 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 962 Human CD48

Swiss-port # P09326 Human CD48 antigen

Gene Symbol CD48
Gene Full Name CD48 molecule
Background CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.
Function Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [UniProt]
Research Area Immune System antibody
Calculated MW 28 kDa

Images (1) Click the Picture to Zoom In

  • ARG53866 anti-CD48 antibody [MEM-102] (PE) FACS image

    Flow Cytometry: Human peripheral blood stained with ARG53866 anti-CD48 antibody [MEM-102] (PE).

Clone References

Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement.

Drbal K et al.
Int Immunol.,  (2007)




Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol.

Stulnig TM et al.
J Biol Chem.,  (1997)




Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102.

Bazil V et al.
Folia Biol (Praha).,  (1989)




The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1.

Korínek V et al.
Immunogenetics.,  (1991)