anti-CD69 antibody [FN50] (PE)

anti-CD69 antibody [FN50] (PE) for Flow cytometry and Human

Developmental Biology antibody; Immune System antibody


Product Description

PE-conjugated Mouse Monoclonal antibody [FN50] recognizes CD69

Tested Reactivity Hu
Tested Application FACS
Specificity The clone FN50 recognizes CD69, an lymphocyte early activation marker.
HLDA IV; WS Code A 91
Host Mouse
Clonality Monoclonal
Clone FN50
Isotype IgG1
Target Name CD69
Antigen Species Human
Immunogen anti-µ-stimulated human B lymphocytes
Conjugation PE
Alternate Names GP32/28; Activation inducer molecule; MLR-3; BL-AC/P26; Leukocyte surface antigen Leu-23; AIM; Early activation antigen CD69; Early T-cell activation antigen p60; EA1; CD antigen CD69; CLEC2C; C-type lectin domain family 2 member C

Application Instructions

Application Suggestion
Tested Application Dilution
FACS20 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 969 Human CD69

Swiss-port # Q07108 Human Early activation antigen CD69

Gene Symbol CD69
Gene Full Name CD69 molecule
Background CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.
Function Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. [UniProt]
Research Area Developmental Biology antibody; Immune System antibody
Calculated MW 23 kDa
PTM Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

Images (1) Click the Picture to Zoom In

  • ARG53891 anti-CD69 antibody [FN50] (PE) FACS image

    Flow Cytometry: Human PHA-activated peripheral blood stained with ARG53891 anti-CD69 antibody [FN50] (PE).

Clone References

CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation.

Henderson NC et al.
J Biol Chem.,  (2004)




Multiple dimeric forms of human CD69 result from differential addition of N-glycans to typical (Asn-X-Ser/Thr) and atypical (Asn-X-cys) glycosylation motifs.

Vance BA et al.
J Biol Chem.,  (1997)