anti-CD7 antibody [MEM-186] (PerCP)

anti-CD7 antibody [MEM-186] (PerCP) for Flow cytometry and Human

Immune System antibody


Product Description

PerCP-conjugated Mouse Monoclonal antibody [MEM-186] recognizes CD7

Tested Reactivity Hu
Tested Application FACS
Specificity The clone MEM-186 reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
HLDA VI; WS Code T 6T-015
Host Mouse
Clonality Monoclonal
Clone MEM-186
Isotype IgG1
Target Name CD7
Antigen Species Human
Immunogen Human acute myelogenous leukaemia cell line KG-1.
Conjugation PerCP
Alternate Names TP41; Tp40; T-cell antigen CD7; CD antigen CD7; T-cell leukemia antigen; LEU-9; T-cell surface antigen Leu-9; GP40

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Note The purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 924 Human CD7

Swiss-port # P09564 Human T-cell antigen CD7

Gene Symbol CD7
Gene Full Name CD7 molecule
Background CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
Function Not yet known. [UniProt]
Research Area Immune System antibody
Calculated MW 25 kDa

Images (1) Click the Picture to Zoom In

  • ARG54275 anti-CD7 antibody [MEM-186] (PerCP) FACS image

    Flow Cytometry: Human peripheral blood cells stained with ARG54275 anti-CD7 antibody [MEM-186] (PerCP).