ARG20947

anti-CD72 antibody [10.1.D2]

anti-CD72 antibody [10.1.D2] for Flow cytometry,Immunoprecipitation,Cellular activation ,Blocking and Mouse

Overview

Product Description Mouse Monoclonal antibody [10.1.D2] recognizes CD72
Tested Reactivity Ms
Tested Application BL, Cell-Act , FACS, IP
Specificity Mouse CD72.1. The clone 10.1.D2 blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
Host Mouse
Clonality Monoclonal
Clone 10.1.D2
Isotype IgG2b, kappa
Target Name CD72
Antigen Species Mouse
Immunogen DBA/2 mouse spleen cells
Conjugation Un-conjugated
Full Name CD72 antigen
Alternate Names CD antigen CD72; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD72b

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
Cell-Act Assay-dependent
FACSAssay-dependent
IPAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 40 kDa

Properties

Form Liquid
Buffer BBS (pH 8.2)
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12517 Mouse CD72

Swiss-port # P21855 Mouse B-cell differentiation antigen CD72

Gene Symbol CD72
Gene Full Name CD72 antigen
Function Plays a role in B-cell proliferation and differentiation. [UniProt]
PTM Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity).