ARG20950

anti-CD72 antibody [10.1.D2] (PE)

anti-CD72 antibody [10.1.D2] (PE) for Flow cytometry,Cellular activation ,Blocking and Mouse

Overview

Product Description PE-conjugated Mouse Monoclonal antibody [10.1.D2] recognizes CD72
Tested Reactivity Ms
Tested Application BL, Cell-Act , FACS
Specificity Mouse CD72.1. The clone 10.1.D2 blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
Host Mouse
Clonality Monoclonal
Clone 10.1.D2
Isotype IgG2b, kappa
Target Name CD72
Species Mouse
Immunogen DBA/2 mouse spleen cells
Conjugation PE
Full Name CD72 antigen
Alternate Names CD antigen CD72; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD72b

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
Cell-Act Assay-dependent
FACS< 0.2 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 40 kDa

Properties

Form Liquid
Buffer PBS, Sodium azide and a stabilizing agent
Preservative Sodium azide
Concentration 0.1 mg/ml
Storage instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12517 Mouse CD72

Swiss-port # P21855 Mouse B-cell differentiation antigen CD72

Gene Symbol CD72
Gene Full Name CD72 antigen
Function Plays a role in B-cell proliferation and differentiation. [UniProt]
PTM Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity).

Images (1) Click the Picture to Zoom In

  • ARG20950 anti-CD72 antibody [10.1.D2] (PE) FACS image

    Flow Cytometry: DBA/2 Mouse splenocytes stained with ARG20950 anti-CD72 antibody [10.1.D2] (PE) and anti-CD19 antibody [6D5] (FITC).