anti-CD79b antibody [HM79-12]

anti-CD79b antibody [HM79-12] for Flow cytometry,Immunoprecipitation,Western blot and Mouse


Product Description Hamster Monoclonal antibody [HM79-12] recognizes CD79b
Tested Reactivity Ms
Tested Application FACS, IP, WB
Specificity Mouse CD79b
Host Hamster
Clonality Monoclonal
Clone HM79-12
Isotype IgG1
Target Name CD79b
Antigen Species Mouse
Immunogen CD79α/CD79β heterodimers purified from Mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231
Conjugation Un-conjugated
Alternate Names B29; B-cell-specific glycoprotein B29; Ig-beta; B-cell antigen receptor complex-associated protein beta chain; Immunoglobulin-associated B29 protein; AGM6; IGB; CD antigen CD79b

Application Instructions

Application Suggestion
Tested Application Dilution
FACS< 1 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Buffer BBS (pH 8.2)
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 15985 Mouse CD79B

Swiss-port # P15530 Mouse B-cell antigen receptor complex-associated protein beta chain

Gene Symbol CD79B
Gene Full Name CD79B antigen
Background The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. [UniProt]
Calculated MW 26 kDa
PTM Phosphorylated on tyrosine upon B-cell activation by SRC-type Tyr-kinases such as BLK, LYN and SYK.

Images (1) Click the Picture to Zoom In

  • ARG22092 anti-CD79b antibody [HM79-12] FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG22092 anti-CD79b antibody [HM79-12] followed by Mouse anti-Hamster IgG1 antibody (PE).