ARG46937
anti-CDC42EP4 antibody
anti-CDC42EP4 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes CDC42EP4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | CDC42EP4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CDC42EP4. |
| Conjugation | Un-conjugated |
| Alternate Names | CDC42EP4; Cdc42 effector protein 4; BORG4; CEP4; Binder of Rho GTPases 4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDC42EP4 |
| Gene Full Name | Cdc42 effector protein 4 |
| Background | The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008] |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts. [UniProt] |
| Cellular Localization | Membrane; Cytoplasm; Cytoskeleton. [UniProt] |
| Calculated MW | 38 kDa |
| PTM | Methylation; Phosphoprotein. [UniProt] |
