ARG46788
anti-CDH1 antibody
anti-CDH1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Monkey
Overview
| Product Description | Goat Polyclonal antibody recognizes CDH1 |
|---|---|
| Tested Reactivity | Hu, Ms, Mk |
| Tested Application | IHC-P, WB |
| Specificity | Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (e.g. HeLa and COS-7). This Ab does not recognize CDH2. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CDH1 |
| Antigen Species | Human |
| Immunogen | Purified Recombinant peptide derived from within residues 601 to 701 of human CDH1 produced in E. coli. |
| Conjugation | Un-conjugated |
| Alternate Names | Uvomorulin; Arc-1; Cadherin-1; E-cadherin; CDHE; CD antigen CD324; ECAD; CAM 120/80; LCAM; Epithelial cadherin; UVO; CD324 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Epitope affinity purified |
| Buffer | PBS, 0.05% Sodium azide and 20% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 20% Glycerol |
| Concentration | 3 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CDH1 |
| Gene Full Name | Cadherin 1 |
| Background | Cadherins comprise a family of Ca-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of cadherins is though to be responsible for binding specificity, transmembrane domains and carboxy terminal domains. The relative short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. |
Images (6) Click the Picture to Zoom In
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ARG46788 anti-CDH1 antibody IHC-P image
Immunohistochemistry: Human breast carcinoma stained with ARG46788 anti-CDH1 antibody at 1:750 dilution.
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ARG46788 anti-CDH1 antibody IHC-P image
Immunohistochemistry: Human pancreas stained with ARG46788 anti-CDH1 antibody at 1:750 dilution.
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ARG46788 anti-CDH1 antibody WB image
Western blot: HeLa, COS-7 stained with ARG46788 anti-CDH1 antibody at 1:500 dilution.
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ARG46788 anti-CDH1 antibody IHC-P image
Immunohistochemistry: Mouse heart stained with ARG46788 anti-CDH1 antibody at 1:750 dilution.
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ARG46788 anti-CDH1 antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG46788 anti-CDH1 antibody at 1:750 dilution.
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ARG46788 anti-CDH1 antibody IHC-P image
Immunohistochemistry: Mouse stomach stained with ARG46788 anti-CDH1 antibody at 1:750 dilution.
