anti-CERK antibody

anti-CERK antibody for Western blot and Human,Mouse

Cell Biology and Cellular Response antibody; Cell Death antibody


Product Description Rabbit Polyclonal antibody recognizes CERK
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CERK
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 487-516 (C-terminus) of Human CERK.
Conjugation Un-conjugated
Alternate Names dA59H18.3; dA59H18.2; hCERK; Ceramide kinase; Lipid kinase 4; LK4; Acylsphingosine kinase; EC

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse heart


Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 223753 Mouse CERK

GeneID: 64781 Human CERK

Swiss-port # Q8K4Q7 Mouse Ceramide kinase

Swiss-port # Q8TCT0 Human Ceramide kinase

Gene Symbol CERK
Gene Full Name ceramide kinase
Background CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]
Function Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. [UniProt]
Cellular Localization Cytoplasm. Membrane; Peripheral membrane protein
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody
Calculated MW 60 kDa

Images (1) Click the Picture to Zoom In

  • ARG54840 anti-CERK antibody WB image

    Western blot: Mouse heart lysate stained with ARG54840 anti-CERK antibody.