ARG46831
anti-CH25H antibody
anti-CH25H antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CH25H |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Target Name | CH25H |
| Antigen Species | Human |
| Immunogen | KLH conjugated synthetic peptide (aa 47-76) from human CH25H |
| Conjugation | Un-conjugated |
| Alternate Names | Cholesterol 25-monooxygenase; h25OH; 1.14.99.38; Cholesterol 25-Hydroxylase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Buffer | PBS and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CH25H |
| Gene Full Name | Cholesterol 25-hydroxylase |
| Background | This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 32 kDa |
| PTM | Glycoprotein. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG46831 anti-CH25H antibody WB image
Western blot: Human brain stained with ARG46831 anti-CH25H antibody.
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ARG46831 anti-CH25H antibody WB image
Western blot: Mouse heart stained with ARG46831 anti-CH25H antibody.
