ARG46961
anti-CKAP2L antibody
anti-CKAP2L antibody for Western blot and Human
Overview
| Product Description | Mouse Polyclonal antibody recognizes CKAP2L |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CKAP2L |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CKAP2L. |
| Conjugation | Un-conjugated |
| Alternate Names | CKAP2L; Cytoskeleton-associated protein 2-like; Radial fiber and mitotic spindle protein; Radmis |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8IYA6 Human Cytoskeleton-associated protein 2-like |
|---|---|
| Gene Symbol | CKAP2L |
| Gene Full Name | Cytoskeleton-associated protein 2-like |
| Background | The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| Function | Microtubule-associated protein required for mitotic spindle formation and cell-cycle progression in neural progenitor cells. [UniProt] |
| Cellular Localization | Cytoplasm; Cytoskeleton. [UniProt] |
| Calculated MW | 84 kDa |
| PTM | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
