ARG46093
anti-CMPK2 antibody
anti-CMPK2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CMPK2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CMPK2 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within aa. 370 - 420 of human CMPK2. |
| Conjugation | Un-conjugated |
| Alternate Names | CMPK2; TYKi; EC 2.7.4.14; UMP-CMPK2; Nucleoside-diphosphate kinase; UMP-CMP kinase 2, mitochondrial; TMPK2; EC 2.7.4.6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CMPK2 |
| Gene Full Name | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial |
| Background | This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
| Function | May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 49.5 kDa |
Images (1) Click the Picture to Zoom In
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ARG46093 anti-CMPK2 antibody WB image
Western blot: Rat lung stained with ARG46093 anti-CMPK2 antibody.
