ARG46970
anti-CNOT11 antibody
anti-CNOT11 antibody for Western blot and Human,Mouse
Overview
| Product Description | Mouse Polyclonal antibody recognizes CNOT11 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CNOT11 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CNOT11. |
| Conjugation | Un-conjugated |
| Alternate Names | CNOT11; CCR4-NOT transcription complex subunit 11; C2orf29 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9CWN7 Mouse CCR4-NOT transcription complex subunit 11 Swiss-port # Q9UKZ1 Human CCR4-NOT transcription complex subunit 11 |
|---|---|
| Gene Symbol | CNOT11 |
| Gene Full Name | CCR4-NOT transcription complex subunit 11 |
| Background | Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Does not seem to be required for complex deadenylase function. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 55 kDa |
| PTM | Methylation. [UniProt] |
